Colletotrichum orbiculare FAM1 Encodes a Novel Woronin Body-Associated Pex22 Peroxin Required for Appressorium-Mediated Plant Infection.
Cucumber anthracnose fungus Colletotrichum orbiculare special form cells called appresoria to penetrate the host. We identified a gene, FAM1, peroxin encoding novel protein that is essential for peroxisome biogenesis and associates with Woronin body (WBS), dense-core vesicles are only found in filamentous ascomycete fungus that serves to maintain cellular integrity. fam1 disrupted mutant can not […]
Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum.
Trypanosoma brucei is the causative agent of diseases that affect 30,000-50,000 people annually. Trypanosoma brucei harbor unique organelles called glycosomes essential for the survival of the parasite, which requires growth under fluctuating environmental conditions. The mechanisms that regulate biogenesis of these organelles are poorly understood. Glycosomes evolutionary related to the peroxisomes, which can proliferate de […]